USMLE United States Medical Licensing Examination

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Showing 7–9 of 20 questions

Question 7

A couple comes for preconceptional genetic counseling because they both have a family history of α-thalassemia. The woman has a minimally decreased hemoglobin concentration. Genetic studies show a single gene deletion. The man has microcytic anemia and a two-gene deletion. If the two-gene deletion is in trans (one deletion on the maternal gene and one deletion on the paternal gene), which of the following percentages of their offspring will have a two-gene deletion?

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  • 0%

  • 25%

  • 50%

  • 75%

  • 100%

Question 8

Normal values for HCO3 are considered:

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  • 15-30 mEq/L

  • 20-35 mEq/L

  • 22-26 mEq/L

  • 24-29 mEq/L

Question 9

Which of the following is caused by a B5 deficiency?

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  • Ectopic pregnancy

  • Nausea

  • Dermatitis

  • Fever