A pulmonary function laboratory routinely tests five subjects as biologic controls. Acceptable instrument performance over time is indicated when measurements
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For each individual are within 2 standard deviations of the mean of previous measurements for each individual.
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For an individual are within 2 standard deviations of the mean of those for the group.
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Of the group as a whole agree with those predicted by linear regression for changes in age.
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Are within the 95% confidence interval predicted for an individual being tested.

